A Single Multipurpose FSH-Blocking Therapeutic for Osteoporosis and Obesity
S. Gera, T.-C. Kuo, F. Korkmaz, D. Sant, V. DeMambro, A. A. Gumerova, K. Sudha, A. Padilla, G. Prevot, J. Munitz, A. Teunissen, M. M. T. van Leent, T. G. J. M. Post, J. C. Fernandes, J. Netto, , M. Zaidi
This paper develops and tests a first-in-class FSH-blocking antibody, MS-Hu6, showing efficacy in preventing obesity and osteoporosis in mice and safety in monkeys.
bioRxiv · Feb 28, 2022 · PreprintPharmacology & Toxicology