A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma
D. Chen, S. K. Varanasi, T. Hara, K. Traina, B. McDonald, Y. Farsakoglu, J. Clanton, S. Xu, T. H. Mann, V. Du, H. K. Chung, Z. Xu, V. Tripple, E. Casillas, S. Ma, , S. M. Kaech
This study identifies a microglia-CD4+ T cell interaction that enhances anti-glioblastoma immunity through IFN-gamma-mediated tumor surveillance and phagocytosis.
bioRxiv · Aug 12, 2022 · PreprintImmunology