Author

K. Traina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

S. M. Kaech· 2 shared Z. Xu· 2 shared A. Kuhlmann-Hogan· 1 shared B. McDonald· 1 shared C. Metallo· 1 shared C. O Connor· 1 shared C. Robles-Oteiza· 1 shared D. Ayeni· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

S. M. Kaech

Mutual co-authors in cluster

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2 papers

Recent·Most cited

EGFR+ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

A. Kuhlmann-Hogan, T. Cordes, Z. Xu, K. Traina, C. Robles-Oteiza, D. Ayeni, E. M. Kwong, S. Levy, M. Nobari, G. Z. Cheng, R. J. Shaw, S. L. Leibel, C. Metallo, K. Politi, S. M. Kaech

This study shows EGFR-mutant lung adenocarcinomas exploit alveolar macrophage metabolism via GM-CSF--PPARγ signaling to support tumor growth and EGFR signaling, suggesting new therapeutic strategies combining statins and PPARγ inhibition.

bioRxiv · Apr 15, 2023 · PreprintImmunology

A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma

D. Chen, S. K. Varanasi, T. Hara, K. Traina, B. McDonald, Y. Farsakoglu, J. Clanton, S. Xu, T. H. Mann, V. Du, H. K. Chung, Z. Xu, V. Tripple, E. Casillas, S. Ma, , S. M. Kaech

This study identifies a microglia-CD4+ T cell interaction that enhances anti-glioblastoma immunity through IFN-gamma-mediated tumor surveillance and phagocytosis.

bioRxiv · Aug 12, 2022 · PreprintImmunology