O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors
Z. Zhang, Z. Huang, M. Awad, M. Elsalanty, J. Cray, L. E. Ball, J. Maynard, A. L. Burlingame, H. Zeng, K. C. Mansky, H.-B. Ruan
This study identifies O-GlcNAc glycosylation as a regulator of bone marrow stromal progenitor fate and niche function, influencing osteogenic/adipogenic differentiation and hematopoiesis.
bioRxiv · Dec 21, 2022Physiology