PhysiologybioRxivPreprint
Atrial t-tubules adopt a specialist developmental state while alterations to Ca2+ buffering maintain systolic Ca2+ during postnatal development
C. E. R. Smith, J. D. Clarke, C. J. Quinn…·K. M. Dibb
This study examines atrial t-tubule development in sheep, showing that despite reduced density in newborns, Ca2+ handling is maintained through increased L-type Ca2+ current and sarcoplasmic reticulum content.
DOI 10.1101/2023.10.01.560329