Author

J. D. Damasceno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. Lapsley· 2 shared R. McCulloch· 2 shared C. A. Marques· 1 shared D. Bartholomeu· 1 shared D. Beraldi· 1 shared E. M. Briggs· 1 shared J. Reis-Cunha· 1 shared K. Crouch· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

C. Lapsley

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivMay 11, 2023

RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei

M. J. Girasol, M. Krasilnikova, C. A. Marques…·R. McCulloch

This study shows RAD51 interacts with RNA-DNA hybrids and repairs DNA breaks at the transcribed VSG in T. brucei, linking RNA-DNA hybrids to antigenic variation.

DOI 10.1073/pnas.2309306120

DNA methylationwhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivOct 10, 2019

Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication

J. D. Damasceno, J. Reis-Cunha, K. Crouch…·R. McCulloch

This study shows that RAD51 and RAD51-related proteins are critical for DNA replication in Leishmania major, with RAD51 specifically impairing DNA synthesis and origin initiation.

DOI 10.1371/journal.pgen.1008828

genetic perturbation / CRISPR

𝕏 PostBluesky