L. Cocquerel

This study identifies HEV ORF2 protein as a cause of glomerulonephritis in hepatitis E patients through immune complex deposition, without detectable viral particles or RNA.

This study characterizes the hepatitis E virus replicase by inserting V5 epitopes into ORF1 and identifying its localization and processing during replication.

This study identifies the endocytic recycling compartment as a site where HEV forms membrane networks, revealing a novel viral factory structure.

This study identifies an Arginine-Rich Motif in the HEV ORF2 capsid protein that regulates its subcellular localization, functionality, and interactions with host cells, revealing its central role in the HEV lifecycle.

This study characterizes the glycosylation of HEV ORF2 protein and its role in viral lifecycle, showing that glycosylation does not affect particle assembly but contributes to antigenicity and nuclear translocation of ORF2i.