Author

K. Seron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Y. Rouille· 4 shared A. Vandeputte· 3 shared J. Dubuisson· 3 shared L. Desmarets· 3 shared P. Brodin· 3 shared S. Belouzard· 3 shared S. Sahpaz· 3 shared C. Riviere· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersMicrobiology

Y. Rouille

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Major Metabolites From Hypericum perforatum L., Hyperforin And Hypericin, Are Both Active Against Human Coronaviruses

I. Raczkiewicz, C. Riviere, P. Bouquet, L. Desmarets, A. Tarricone, C. Camuzet, N. Francois, G. Lefevre, J. Samaillie, F. Silva Angulo, C. Robil, F. Trottein, S. Sahpaz, J. D. Dubuisson, S. Belouzard, , K. Seron

This study shows that hyperforin from Hypericum perforatum inhibits multiple coronaviruses, including SARS-CoV-2, with antiviral activity confirmed in human cells and potential for combination therapy with remdesivir.

bioRxiv · Apr 9, 2024 · PreprintMicrobiology

A photoactivable natural product with broad antiviral activity against enveloped viruses including highly pathogenic coronaviruses

T. Meunier, L. Desmarets, S. Bordage, M. Bamba, K. Hervouet, Y. Rouille, N. Francois, M. Decossas, F. H. Tra Bi, O. Lambert, J. Dubuisson, S. Belouzard, S. Sahpaz, K. Seron

This paper identifies pheophorbide a as a light-activated natural antiviral effective against SARS-CoV-2, MERS-CoV, and other enveloped viruses by inhibiting viral entry and replication.

bioRxiv · Jul 9, 2021Microbiology

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice

S. Belouzard, A. Machelart, V. Sencio, T. Vausselin, E. Hoffmann, N. Deboosere, Y. Rouille, L. Desmarets, K. Seron, A. Danneels, C. Robil, L. Belloy, C. Moreau, C. Piveteau, A. Biela, , J. Dubuisson

This paper identifies clofoctol as an antiviral against SARS-CoV-2, showing it inhibits viral replication and reduces lung pathology in mice.

bioRxiv · Jun 30, 2021 · PreprintMicrobiology

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus Is a New Inhibitor of Hepatitis C Virus Replication

M.-E. Sahuc, R. Sahli, C. Riviere, V. Pene, M. Lavie, A. Vandeputte, P. Brodin, A. Rosenberg, J. D. Dubuisson, R. Ksouri, Y. Rouille, S. Sahpaz, K. Seron

This paper identifies dehydrojuncusol, a natural compound from Juncus maritimus, as a new inhibitor of HCV replication that targets NS5A and is effective against DAA-resistant variants.

bioRxiv · Nov 14, 2018Microbiology

Theaflavins, polyphenols of black tea, inhibit entry of hepatitis C virus

P. Chowdhury, M.-E. Sahuc, Y. Rouille, A. Vandeputte, P. Brodin, M. Goswami, T. Bandyopadhyay, J. Dubuisson, K. Seron

This study shows that theaflavins from black tea inhibit HCV entry in a dose-dependent manner and show additive effects with existing antivirals.

bioRxiv · May 17, 2018Microbiology