Mechanosensitive FHL2 tunes endothelial function
S. Seetharaman, J. Devany, H. R. Kim, E. J. van Bodegraven, T. Chmiel, S. Tzu-Pin, W.-h. Chou, Y. Fang, M. Gardel
This study identifies FHL2 as a mechanosensitive protein that drives endothelial dysfunction under athero-prone flow conditions by modulating adherens junctions and Rho-ROCK signaling.
bioRxiv · Jun 16, 2024 · PreprintCell Biology