Intrauterine Growth-Restricted Pregnant Rats, from Hypertensive Placental Ischemic Dams Display Preeclamptic-like Symptoms: A New Rodent Model of Preeclampsia
J. Smith, M. Powell, W. Cromartie, S. Smith, K. Jones, A. Castillo, J. Shaw, J. Editone, A. Howard-Cunningham, R. Tatum, A. N. Smith, B. Fisher, G. W. Booz, M. W. CUNNINGHAM
This study establishes a new rodent model of preeclampsia by inducing intrauterine growth restriction in pregnant rats, showing elevated blood pressure and oxidative stress.
bioRxiv · Feb 7, 2024 · PreprintPhysiology