Antimicrobial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase
B. Obeng, L. J. Bennett, B. E. West, D. J. Wagner, P. J. Fleming, M. N. Tasker, M. K. Lorenger, D. R. Smith, T. Systuk, S. M. Plummer, J. Eom, M. D. Paine, C. T. Frangos, M. P. Wilczek, J. K. Shim, , J. A. Gosse
This study shows that cetylpyridinium chloride inhibits mast cell function by disrupting tyrosine phosphorylation of Syk kinase and LAT, without affecting Lyn kinase.
bioRxiv · Jul 4, 2024 · PreprintPharmacology & Toxicology