Author

J. Force

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. V. DiMarco· 1 shared B. A. Hanks· 1 shared B. McKinney· 1 shared C. Keddy· 1 shared C. Z. Beach· 1 shared E. Aguero· 1 shared J. V. Alvarez· 1 shared J. Xie· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. V. DiMarco

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2 papers

Recent·Most cited

Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors

S. R. Iyer, K. Nusser, K. Jones, P. Shinde, C. Z. Beach, C. Keddy, E. Aguero, J. Force, U. Shinde, M. A. Davare

The paper identifies oncogenic ROS1 missense mutations that are sensitive to tyrosine kinase inhibitors, showing their potential as therapeutic targets.

EMBO Molecular Medicine · Oct 11, 2023Peer-reviewedCancer Biology

APOBEC mutagenesis inhibits breast cancer growth through induction of a T cell-mediated antitumor immune response

A. V. DiMarco, X. Qin, S. Van Alsten, B. McKinney, N. M. G. Garcia, J. Force, B. A. Hanks, M. A. Troester, K. Owzar, J. Xie, J. V. Alvarez

This study shows that APOBEC mutagenesis in breast cancer promotes T cell-mediated antitumor immunity, leading to tumor growth inhibition and sensitivity to checkpoint inhibitors.

bioRxiv · Feb 13, 2021Cancer Biology