Author

S. Van Alsten

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. V. DiMarco· 1 shared B. A. Hanks· 1 shared B. McKinney· 1 shared J. Force· 1 shared J. V. Alvarez· 1 shared J. Xie· 1 shared K. Owzar· 1 shared M. A. Troester· 1 shared

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2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. V. DiMarco

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1 paper

Recent·Most cited

Cancer BiologybioRxivFeb 13, 2021

APOBEC mutagenesis inhibits breast cancer growth through induction of a T cell-mediated antitumor immune response

A. V. DiMarco, X. Qin, S. Van Alsten…·J. V. Alvarez

This study shows that APOBEC mutagenesis in breast cancer promotes T cell-mediated antitumor immunity, leading to tumor growth inhibition and sensitivity to checkpoint inhibitors.

DOI 10.1158/2326-6066.cir-21-0146

mouseexperimental assay

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