Author

J. Freitas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Fusco· 1 shared A. Garabedian· 1 shared A. I. Varela· 1 shared B. Moiraghi· 1 shared C. Furtado· 1 shared C. Pavlovsky· 1 shared D. Koile· 1 shared F. DAlessio· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Fusco

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

miRNome profiling of clonal stem cells in Ph+ CML

M. S. Ruiz, M. B. Sanchez, S. Bonecker, C. Furtado, D. Koile, P. Yankilevich, S. Cranco, M. d. R. Custidiano, J. Freitas, B. Moiraghi, M. A. Perez, C. Pavlovsky, A. I. Varela, V. Ventriglia, J. C. Sanchez Avalos, , M. Bianchini

This study profiles the miRNome of CML leukemic stem cells and compares it to normal stem cells and healthy donors, identifying global miRNA decreases and metabolic pathway associations.

bioRxiv · Mar 16, 2020Cancer Biology

Suramin potently inhibits binding of the mammalian high mobility group protein AT-hook 2 to DNA

L. Su, N. Bryan, S. Battista, J. Freitas, A. Garabedian, F. DAlessio, M. Romano, F. Falanga, A. Fusco, L. Kos, J. Chambers, F. Fernandez-Lima, P. P. Chapagain, S. Vasile, L. Smith, F. Leng

This study identifies suramin as a potent inhibitor of HMGA2-DNA binding, showing it disrupts HMGA2 function and induces differentiation of brain tumor stem cells.

bioRxiv · Nov 12, 2019 · PreprintBiochemistry