J. G. Sanchez

This paper introduces a microarray 3D bioprinting platform with pillar and perfusion plates for high-throughput human organoid culture and analysis.

The paper shows that substrate energy dissipation suppresses YAP mechanosensing more than stiffness cues in cell mechanotransduction.

This study shows that enteroendocrine cells regulate crypt metabolism and intestinal stem cell function by transmitting nutrient status to the stem cell niche.

This study shows that a high fat diet rapidly alters intestinal epithelial cell function and composition within days, including stress responses and shifts in metabolic and absorptive capabilities.

This study identifies peptide YY as a regulator of ion-coupled nutrient absorption in the small intestine, showing its therapeutic potential for malabsorption.