Tissue- and sex-specific DNA damage tracks aging in rodents and humans
A. Guilbaud, F. Ghanegolmohammadi, Y. Wang, J. Leng, A. Kreymerman, J. Gamboa Varela, J. Garbern, H. Elwell, F. Cao, E. M. Ricci-Blair, C. Liang, S. Balamkundu, C. Vidoudez, M. S. DeMott, K. Bedi, , P. C. Dedon
This study identifies DNA damage patterns across tissues and sexes in rodents and humans, revealing age- and sex-dependent variations in DNA adducts and their potential as disease markers.
bioRxiv · Nov 28, 2022 · PreprintBiochemistry