Author

J. Leng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:chicken / avian· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

D. Bialy· 2 shared H. Shelton· 2 shared K. Chrzastek· 2 shared R. La Ragione· 2 shared A. A. Palmer· 1 shared A. Barkley-Levenson· 1 shared A. Cleasby· 1 shared A. Curd· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. Bialy

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Investigation of 3D Printed Bioresorbable Vascular Scaffold Crimping Behavior

C. Collins, J. Leng, R. Fu, Y. Ding, G. Ameer, C. Sun

The paper develops a simulation tool using ABAQUS to analyze the crimping behavior of 3D-printed bioresorbable vascular scaffolds, enabling faster design evaluation than experimental testing.

bioRxiv · Oct 26, 2023Bioengineering

Alteration of the chicken upper respiratory microbiota following H9N2 avian influenza virus infection

T. Davis, D. Bialy, J. Leng, R. La Ragione, H. Shelton, K. Chrzastek

This study examines how H9N2 avian influenza virus infection affects the upper respiratory microbiota diversity and composition in chickens, finding reduced alpha diversity and persistent microbiota changes during recovery.

bioRxiv · Aug 8, 2023 · PreprintMicrobiology

Mechanically stimulated osteocytes maintain tumor dormancy in bone metastasis of non-small cell lung cancer by releasing small extracellular vesicles

J. Xie, Y. Xu, X. Liu, L. Long, J. Chen, C. Huang, Y. Shao, Z. Cai, Z. Zhang, R. Zhou, J. Leng, X. Bai, Q. Song

This study shows that mechanically stimulated osteocytes release extracellular vesicles containing microRNAs that inhibit NSCLC cell proliferation and bone metastasis progression.

bioRxiv · Jun 14, 2023Cancer Biology

Tissue- and sex-specific DNA damage tracks aging in rodents and humans

A. Guilbaud, F. Ghanegolmohammadi, Y. Wang, J. Leng, A. Kreymerman, J. Gamboa Varela, J. Garbern, H. Elwell, F. Cao, E. M. Ricci-Blair, C. Liang, S. Balamkundu, C. Vidoudez, M. S. DeMott, K. Bedi, , P. C. Dedon

This study identifies DNA damage patterns across tissues and sexes in rodents and humans, revealing age- and sex-dependent variations in DNA adducts and their potential as disease markers.

bioRxiv · Nov 28, 2022 · PreprintBiochemistry

An RNA binding protein, RNP1A, works with Contractility Kit proteins to facilitate macropinocytosis

Y. Liu, J. Leng, L. T. Nguyen, D. N. Robinson

This study identifies RNP1A as an RNA-binding protein that interacts with Contractility Kit proteins to support macropinocytosis in Dictyostelium discoideum.

bioRxiv · Jul 8, 2022 · PreprintCell Biology

Low pathogenic avian influenza virus infection retards colon microbiome diversification in two different chicken lines

K. Chrzastek, J. Leng, M. K. Zakaria, D. Bialy, R. La Ragione, H. Shelton

This study shows that low pathogenic avian influenza virus infection reduces colon microbiome diversity in two chicken breeds, delaying its recovery.

bioRxiv · Mar 15, 2021Microbiology

Nanoscale pattern extraction from relative positions of sparse 3D localisations

A. Curd, J. Leng, R. Hughes, A. Cleasby, B. Rogers, C. Trinh, M. Baird, Y. Takagi, C. Tiede, C. Sieben, S. Manley, T. Schlichthaerle, R. Jungmann, J. Ries, H. Shroff, M. Peckham

The paper introduces a method to extract high-resolution ordered features from localisation microscopy data by analyzing relative molecular positions, applied to infer ultrastructure of various biological structures.

bioRxiv · Feb 13, 2020Cell Biology