Overcoming the speed limit of four-way DNA branch migration with bulges in toeholds
F. Smith, A. Sengar, G.-B. V. Stan, T. E. Ouldridge, M. Stevens, J. Goertz, W. Bae
This paper introduces a method to enhance four-way DNA exchange reaction kinetics by adding bulges to toeholds, making it faster and more efficient, closer to three-way reactions.
bioRxiv · May 15, 2023 · PreprintBiophysics