Author

J. Guerin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Konijnenberg· 1 shared A. Pluckthun· 1 shared A. Vieille· 1 shared B. Dreier· 1 shared C. Berge· 1 shared C. Lettl· 1 shared E. Del Nero· 1 shared F. Jacob-Dubuisson· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. Konijnenberg

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2 papers

Recent·Most cited

Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

M. Blanc, C. Lettl, J. Guerin, A. Vieille, S. Furler, S. Briand-Schumacher, B. Dreier, C. Berge, A. Pluckthun, S. Vadon-Le Goff, R. Fronzes, P. Rousselle, W. Fischer, L. TERRADOT

This study characterizes the structure and function of CagI in Helicobacter pylori's type IV secretion system and identifies DARPins that inhibit CagA translocation.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology

Large-scale conformational changes of FhaC provide insights into the two-partner secretion mechanism

G. Sicoli, A. Konijnenberg, J. Guerin, S. Hessmann, E. Del Nero, O. Hernandez-Alba, S. Lecher, G. Rouaut, L. Mueggenburg, H. Vezin, S. CIANFERANI, F. Sobott, R. Schneider, F. Jacob-Dubuisson

The paper investigates conformational changes in FhaC, a TpsB transporter, revealing how it facilitates protein secretion without external energy sources through intrinsic dynamics.

bioRxiv · Nov 9, 2021Biophysics