Author

E. Del Nero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. BECHARA· 3 shared C. Leyrat· 3 shared S. Granier· 3 shared S. Fontanel· 2 shared S. Jeannot· 2 shared T. Durroux· 2 shared X. Cong· 2 shared A. Konijnenberg· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiochemistry

C. BECHARA

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Conformational dynamics underlying Atypical Chemokine Receptor 3 activation

O. Otun, C. Aljamous, E. Del Nero, M. Arimont-Segura, R. Bosma, B. Zarzycka, T. Girbau, C. Leyrat, C. de Graaf, R. Leurs, T. Durroux, S. Granier, X. Cong, C. BECHARA

This study investigates the conformational dynamics of ACKR3 activation using HDX-MS and molecular dynamics simulations, revealing key structural changes and ligand binding mechanisms.

bioRxiv · Jul 17, 2023 · PreprintBiochemistry

Large-scale conformational changes of FhaC provide insights into the two-partner secretion mechanism

G. Sicoli, A. Konijnenberg, J. Guerin, S. Hessmann, E. Del Nero, O. Hernandez-Alba, S. Lecher, G. Rouaut, L. Mueggenburg, H. Vezin, S. CIANFERANI, F. Sobott, R. Schneider, F. Jacob-Dubuisson

The paper investigates conformational changes in FhaC, a TpsB transporter, revealing how it facilitates protein secretion without external energy sources through intrinsic dynamics.

bioRxiv · Nov 9, 2021Biophysics

Discovery and mechanism of action of small molecule inhibitors of ceramidases

S. Granier, R. D. Healey, E. Saied, X. Cong, G. Karsai, L. Gabellier, J. Saint-Paul, E. Del Nero, S. Jeannot, M. Drapeau, S. Fontanel, D. Maurel, S. Basu, C. LEYRAT, G. Bossis, , C. Arenz

The paper discovers small molecule inhibitors of alkaline ceramidase 3 using fluorescent substrates and characterizes their mechanism of action.

bioRxiv · Jun 15, 2021Biochemistry

Mechanisms of GPCR hijacking by Staphylococcus aureus

C. M. Grison, C. Leyrat, P. Lambey, S. Jeannot, E. Del Nero, S. Fontanel, F. Peysson, J. Heuninck, R. Sounier, T. Durroux, S. Granier, C. Bechara

This study investigates how Staphylococcus aureus leukotoxins HlgA and HlgB interact with ACKR1, altering its structure and function to aid bacterial growth and immune evasion.

bioRxiv · Feb 8, 2021 · PreprintBiochemistry