Stepwise transmigration cascade of T and B cells through the perivascular channel in lymph node high endothelial venules
K. Choe, J. Moon, S. Y. Lee, E. Song, J. H. Back, J.-H. Song, Y.-M. Hyun, K. Uchimura, P. Kim
This study uses intravital imaging to show T and B cells migrate through HEVs via distinct post-luminal steps involving ECs and FRCs, with T and B cells sharing trans-FRC hot spots but not trans-EC ones.
bioRxiv · Dec 20, 2020Immunology