P. Kim

Enhancing reproducibility and decentralization in single cell research with biocytometry

This study evaluates biocytometry's performance in a decentralized setting, showing its ability to accurately count rare cells across multiple labs with minimal training.

Label-free structural imaging of plant roots and microbes using third-harmonic generation microscopy

This study uses third-harmonic generation microscopy to image plant roots and microbes in their natural environment without labels.

Labeling Natural Killer cells with superparamagnetic iron oxide nanoparticles for detection by preclinical and clinical-scale magnetic particle imaging

This study labels NK cells with iron oxide nanoparticles and demonstrates their detection using magnetic particle imaging in preclinical and clinical settings.

Glycolytic oscillations under periodic drivings

This study examines how periodic glucose injection affects glycolytic oscillations using a dynamical systems approach, revealing entrainment and chaotic behavior under specific driving conditions.

An Aging-Susceptible Circadian Rhythm Controls Cutaneous Antiviral Immunity

This study identifies a circadian rhythm that regulates antiviral immunity in skin, showing that aging disrupts this rhythm and that circadian enhancers can restore antiviral defenses.

A collaborative approach to improving representation in viral genomic surveillance

This paper develops a collaborative genomic surveillance model to improve representation in rural and minority communities, generating over 1,000 SARS-CoV-2 genomes and identifying new variants.

Fully Automated Multi-Grid Cryo-EM Screening using Smart Leginon

Smart Leginon automates cryo-EM grid screening, reducing operator time from 6 hours to <10 minutes and improving throughput.

Changes of Mutations and Copy-number and Enhanced Cell Migration during Breast Tumorigenesis

This study identifies mutations and copy-number variations in breast tumorigenic cells and shows that ECM-mimetic platforms enhance their migration.

Hematopoietic stem and progenitor cells integrate Bacteroides-derived innate immune signals to promote gut tissue repair

This study shows that Bacteroides activates HSPCs in the BM during acute gut inflammation to promote tissue repair, but impairs HSC function in chronic inflammation and aging.

Widespread multi-targeted therapy resistance via drug-induced secretome fucosylation

This study identifies drug-induced secretome fucosylation as a mechanism of resistance to targeted therapies across multiple cancers.

Stepwise transmigration cascade of T and B cells through the perivascular channel in lymph node high endothelial venules

This study uses intravital imaging to show T and B cells migrate through HEVs via distinct post-luminal steps involving ECs and FRCs, with T and B cells sharing trans-FRC hot spots but not trans-EC ones.

A VP2/3-derived peptide exhibits potent antiviral activity against BK and JC polyomaviruses by targeting a novel VP1 binding site

The paper identifies a VP2/3-derived peptide that inhibits BK and JC polyomaviruses by binding to a novel VP1 pore site, showing potent antiviral activity with low nanomolar affinity.