Cell Membranes Sustain Phospholipid Imbalance Via Cholesterol Asymmetry
M. Doktorova, J. L. Symons, X. Zhang, H.-Y. Wang, J. Schlegel, J. H. Lorent, F. A. Heberle, E. Sezgin, E. Lyman, K. R. Levental, I. Levental
The paper reveals that mammalian plasma membranes have phospholipid imbalances due to cholesterol asymmetry, affecting membrane permeability and protein localization.
bioRxiv · Jul 30, 2023Biophysics