Author

J. Harper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. G. Patel· 1 shared C. Long· 1 shared C. Savage· 1 shared C. W. LaFlamme· 1 shared G. Youssef· 1 shared H. Sheppard· 1 shared H. Tagoe· 1 shared H.-M. Lee· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. G. Patel

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2 papers

Recent·Most cited

An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs.

R. H. Chapple, X. Liu, S. Natarajan, M. I. M. Alexander, Y. Kim, A. G. Patel, C. W. LaFlamme, M. Pan, W. C. Wright, H.-M. Lee, Y. Zhang, M. Lu, S. C. Koo, C. Long, J. Harper, , P. Geeleher

The paper compares mesenchymal-like gene expression programs in neuroblastoma preclinical models and patient tumors using single-cell RNA-seq and identifies chemotherapy-induced changes in PDX and GEMM.

bioRxiv · Apr 13, 2023Cancer Biology

Chronic activation of Toll-like receptor 2 induces an ichthyotic skin phenotype

H. Tagoe, S. Hassan, G. Youssef, K. Mills, J. Harper, R. F. O'Shaughnessy

This study identifies TLR2 activation as a common mechanism in ichthyosis, showing it induces hyperkeratosis and alters keratin expression through NFκB and Gata3 pathways.

bioRxiv · Jun 6, 2022Cell Biology