Cell BiologybioRxivPreprint
p53 secures the normal behavior of H3.1 histone in the nucleus by regulating nuclear phosphatidic acid and EZH2 during the G1/S phase
T. Oikawa, J. Hasegawa, H. Handa…·H. Sabe
This study shows p53 regulates H3.1 histone behavior during G1/S phase by modulating nuclear phosphatidic acid and EZH2 levels, preventing H3.1 from being trimethylated at the nuclear envelope.
DOI 10.1101/2023.06.27.545208