Author

J. I. Ayers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Butte· 1 shared A. Laeremans· 1 shared A. M. Crown· 1 shared B. L. Roberts· 1 shared D. Borchelt· 1 shared D. R. Wong· 1 shared H. Brown· 1 shared J. C. Lee· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. J. Butte

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics

D. R. Wong, J. Conrad, N. Johnson, J. I. Ayers, A. Laeremans, J. C. Lee, J. Lee, S. B. Prusiner, S. Bandyopadhyay, A. J. Butte, N. A. Paras, M. J. Keiser

This paper introduces a deep learning method to improve high-content screening for Alzheimer's disease therapeutics by generating predicted fluorescent signals from alternative markers.

bioRxiv · Jan 8, 2021Pharmacology & Toxicology

Loss of charge at solvent exposed Lys residues does not induce the aggregation of superoxide dismutase 1

K. Crosby, A. M. Crown, B. L. Roberts, H. Brown, J. I. Ayers, D. Borchelt

This study shows that losing positive charge at surface lysine residues in SOD1 does not cause misfolding or aggregation, suggesting these mutations are not disease drivers.

bioRxiv · Apr 14, 2018Biochemistry