Cell BiologybioRxivPreprint
Ambra1 haploinsufficiency results in metabolic alterations and exacerbates age-associated retinal degeneration
I. Ramirez-Pardo, B. Villarejo-Zori, J. I. Jimenez-Loygorri…·P. Boya
This study shows that reduced Ambra1 levels in mice lead to metabolic issues and faster retinal degeneration, suggesting autophagy's role in protecting against aging-related vision loss.
DOI 10.1101/2022.02.04.476630