Author

J. J. Nirschl

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Beck· 1 shared B. Bui· 1 shared C. K. Petritsch· 1 shared D. Hambardzumyan· 1 shared D. Panovska· 1 shared E. Nasajpour· 1 shared G. A. Grant· 1 shared J. M. Mulcahy Levy· 1 shared

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2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Beck

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1 paper

Recent·Most cited

Cancer BiologybioRxivFeb 3, 2023

BRAF/MEK Inhibition Induces Cell State Transitions Boosting Immune CheckpointSensitivity in BRAFV600E-mutant Glioma

Y. L. Xing, D. Panovska, J.-W. Park…·C. K. Petritsch

This study shows that BRAF/MEK inhibition induces cell state transitions in BRAFV600E-mutant gliomas, leading to PD-L1 upregulation and immune evasion, which can be overcome by combining with immune checkpoint inhibition.

DOI 10.1016/j.xcrm.2025.102183

mouseproteomics

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