BiochemistrybioRxiv
Convergent Hybrid Phase Ligation Strategy for Efficient Total Synthesis of Large Proteins Demonstrated for 212-residue Linker Histone H1.2
Z. Z. Hong, R. R. Yu, X. Zhang…·J. J. Ottesen
The paper develops a convergent hybrid phase ligation strategy for synthesizing large proteins, demonstrating its effectiveness with the 212-residue histone H1.2.
DOI 10.1002/pep2.24323