MicrobiologybioRxiv
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors
M. Saldivia, S. P. S. Rao, E. Fang…·J. C. Mottram
This study identifies CLK1 as a novel drug target in Trypanosoma brucei by showing its essential role in kinetochore function and cell survival through kinase inhibition.
DOI 10.1038/s41564-020-0745-6