CXCL12 in late-stage osteoblasts and osteocytes is required for load induced bone formation in mice
P. Cabahug-Zuckerman, C. Liu, P. Atria, C. Cai, E. Fang, S. Qureshi, R. Rooklin, C. Ponce, C. Morocho, A. B. Castillo
This paper shows that CXCL12 in late-stage osteoblasts and osteocytes is essential for load-induced bone formation in mice, as its absence reduces bone formation and recombinant CXCL12 rescues this phenotype.
bioRxiv · Aug 25, 2022 · PreprintCell Biology