PhysiologyCirculation ResearchPeer-reviewed
Necessary Role of Acute Ceramide Formation in The Human Microvascular Endothelium During Health and Disease
G. SenthilKumar, B. Katunaric, Z. Zirgibel…·J. K. Freed
This study shows that acute ceramide formation via NSmase is essential for NO signaling in human microvascular endothelium, with distinct mechanisms in healthy individuals and CAD patients.
DOI 10.1161/circresaha.123.323445