Sugar transporter Slc37a2 regulates bone metabolism via a dynamic tubular lysosomal network in osteoclasts
P. Y. Ng, A. Ribet, Q. Guo, B. Mullin, J. Tan, E. Landao-Bassonga, S. Stephens, K. Chen, L. Abudulai, M. Bollen, E. Nguyen, J. Kular, J. Papadimitriou, K. Soe, R. Teasdale, , N. Pavlos
This study identifies Slc37a2 as a sugar transporter in osteoclast secretory lysosomes, showing its role in bone metabolism through dynamic tubular networks and its impact on bone mass.
bioRxiv · Apr 28, 2022 · PreprintCell Biology