GIP receptor reduces osteoclast activity and improves osteoblast survival by activating multiple signaling pathways
M. S. Hansen, K. Soe, L. L. Christensen, P. Fernandez-Guerra, N. W. Hansen, R. A. Wyatt, C. Martin, R. S. Hardy, T. L. Anderson, J. B. Olesen, S. Overgaard, B. Hartmann, M. M. Rosenkilde, M. Kassem, A. Rauch, , M. Frost
This study shows GIP reduces osteoclast activity and improves osteoblast survival through multiple signaling pathways, suggesting GIPR agonism could treat osteoporosis.
bioRxiv · Jul 2, 2022Cell Biology