MicrobiologybioRxiv
Cofactor selectivity in methylmalonyl-CoA mutase, a model cobamide-dependent enzyme
O. M. Sokolovskaya, K. C. Mok, J. D. Park…·M. E. Taga
This study investigates how structural variations in cobamides affect the binding selectivity of methylmalonyl-CoA mutase, showing that in vitro binding correlates with in vivo cobamide dependence.
DOI 10.1128/mbio.01303-19