Single cell reconstruction of human basal cell diversity in normal and IPF lung.
G. Carraro, A. Mulay, C. Yao, T. Mizuno, B. Konda, M. Petrov, D. Lafkas, J. R. Arron, C. M. Hogaboam, P. Chen, D. Jiang, P. Noble, S. H. Randell, J. L. McQualter, B. Stripp
The paper uses single-cell RNA sequencing to analyze basal cell diversity in normal and IPF lung, finding increased secretory primed basal cells in IPF and roles for NOTCH2 and NOTCH3 in their regulation.
bioRxiv · Jun 19, 2020Cell Biology