Animal Behavior & CognitionbioRxivPreprint
Ketamine decreases HPA axis reactivity to a novel stressor in male but not female mice
C. J. Johnston, P. F. Fitzgerald, J. S. Gewarges…·J. L. Spencer-Segal
This study investigates whether ketamine's antidepressant effect depends on HPA axis function, finding that ketamine reduces corticosterone response to a stressor only in male mice.
DOI 10.1101/2021.06.29.450387