C. Meneses

Sup4h5-L19 activation tagging line partially restores root hair growth in p4h5 mutant by introducing small transcriptomic changes in Arabidopsis thaliana

The paper identifies an activation-tagging line that partially restores root hair growth in a p4h5 mutant by altering gene expression, particularly at low temperatures.

Two antagonistic gene regulatory networks drive Arabidopsis root hair growth at low temperature

This paper identifies two opposing gene regulatory networks that control root hair growth in Arabidopsis at low temperature, revealing their role in integrating environmental and internal signals.

Transcriptomic reprogramming in a susceptible Phaseolus vulgaris L. variety during Pseudomonas syringae attack: The key role of homogalacturonan methylation

This study investigates transcriptomic changes in a susceptible common bean variety during Pseudomonas syringae infection, identifying homogalacturonan methylation as a key factor in susceptibility.

Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis

This study shows that centrin-deficient L. mexicana parasites protect against Old World visceral leishmaniasis in a hamster model by reducing parasite burden and altering cytokine responses.

Genetic exchange in Leishmania is facilitated by IgM natural antibodies

This study shows IgM antibodies facilitate Leishmania genetic hybridization in vitro and in vivo, leading to full genome hybrids and increased genetic exchange.

Transcriptomic analysis of the C3-CAM transition in Cistanthe longiscapa, a drought tolerant plant in the Atacama Desert

The paper analyzes transcriptomic differences in Cistanthe longiscapa across an arid gradient to understand the molecular basis of CAM photosynthesis transition.

Apoplastic class III peroxidases PRX62 and PRX69 regulate ROS-homeostasis and cell wall associated extensins linked to root hair growth at low-temperature in Arabidopsis thaliana

The paper identifies PRX62 and PRX69 as apoplastic peroxidases that regulate ROS homeostasis and cell wall extensin insolubilization, affecting root hair growth at low temperatures in Arabidopsis thaliana.

Preclinical validation of a second generation leishmanization vaccine against vector transmitted fatal visceral leishmaniasis

This study evaluates the protective efficacy of a CRISPR-edited Leishmania major strain against visceral leishmaniasis in hamsters and shows it induces a pro-inflammatory immune response and prevents disease.

Binding of Leishmania infantum LPG to the midgut is not sufficient to define vector competence in Lutzomyia longipalpis sand flies

This study shows that Leishmania infantum LPG is not necessary for midgut retention in permissive sand flies but protects certain strains from blood digestion toxins.

A Second Generation Leishmanization Vaccine with a Markerless Attenuated Leishmania major Strain using CRISPR gene editing

This paper describes a CRISPR-edited Leishmania major strain for a second-generation leishmanization vaccine that is marker-free and safe, showing protection in mice comparable to traditional leishmanization.

Leishmania infection induces a limited differential gene expression in the sand fly midgut

This study uses RNA-Seq to analyze midgut gene expression changes in sand flies infected with Leishmania, finding limited differential expression with stage-specific effects.

Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers

The paper identifies stage-specific gene expression markers in Leishmania infantum during its development in the sand fly vector using RNAseq and differential expression analysis.

Complete genome of a Measles virus from Roraima state, Brazil

The paper reports the complete genome sequencing of a measles virus isolate from Brazil, placing it phylogenetically with samples from other countries and noting it as the first wild-type measles genome from Latin America.