DoUble resin Casting micro computed Tomography (DUCT) reveals biliary and vascular pathology in a mouse model of Alagille syndrome
S. Hankeova, J. Salplachta, T. Zikmund, M. Kavkova, N. Van Hul, A. Brinek, V. Smekalova, J. Laznovsky, J. Jaros, V. Bryja, U. Lendahl, E. Ellis, E. Hannezo, J. Kaiser, E. R. Andersson
The paper introduces DUCT, a method to image and quantify 3D biliary and vascular structures in mouse livers, revealing novel phenotypes in Alagille syndrome models and human patients.
bioRxiv · Nov 21, 2019Pathology