E. Hannezo

Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts

The paper shows cortical Actin flows, driven by Myosin-2 depletion, mediate E-cadherin redistribution and cell contact formation.

Interplay between mechanochemical patterning and glassy dynamics in cellular monolayers

The paper investigates how mechanochemical interactions influence cellular monolayer dynamics, showing that a balance between active forces and mechanochemical couplings leads to spatiotemporal patterns.

Chiral and nematic phases of flexible active filaments

The paper investigates how filament flexibility, density, and chirality influence the formation of chiral and nematic phases in FtsZ filaments during bacterial cell division.

Geometry-driven migration efficiency of autonomous epithelial cell clusters

This study investigates how the geometry of microstripes affects the migration efficiency of epithelial cell clusters and identifies interaction rules governing their movement in complex environments.

Dual role of Pectin Methyl Esterase activity in the regulation of plant cell wall biophysical properties.

This study shows acidification induces cell elongation via cell wall relaxation and PME activity regulates cell wall stiffness in a calcium-dependent manner, essential for hypocotyl elongation.

Sinking the way: a dual role for CCR7 in collective leukocyte migration

This study shows CCR7 has a dual role in leukocyte migration by both sensing and consuming its ligand to generate and modulate chemotactic gradients.

Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation

This study shows that epithelial monolayers sense substrate curvature through changes in cell and nuclear shape, thickness, and YAP distribution, mediated by active cell mechanics and nuclear mechanoadaptation.

Theory of branching morphogenesis by local interactions and global guidance

This study develops a theoretical framework to analyze how global and local cues influence branching morphogenesis, using zebrafish innervation as a model system.

Multi-tier mechanics control stromal adaptations in swelling lymph nodes

The paper investigates how lymph nodes accommodate size increases during immune challenges by analyzing biomechanical adaptations of fibroblastic reticular cells and fibroblasts.

Theory of mechano-chemical patterning and optimal migration in cell monolayers

The paper develops a biophysical theory explaining mechano-chemical patterning in cell monolayers and shows how it optimizes collective migration.

Stem cell lineage survival as a noisy competition for niche access

The paper develops a stochastic competition model for stem cell niche access and validates it across multiple tissue datasets.

DoUble resin Casting micro computed Tomography (DUCT) reveals biliary and vascular pathology in a mouse model of Alagille syndrome

The paper introduces DUCT, a method to image and quantify 3D biliary and vascular structures in mouse livers, revealing novel phenotypes in Alagille syndrome models and human patients.

Abscission couples cell division to embryonic stem cell fate

The paper shows that abscission couples cell division to exit from naive pluripotency in mouse embryonic stem cells.

Constrained actin dynamics emerges from variable compositions of actin regulatory protein complexes

The paper shows that heterogeneous actin regulatory complexes can produce stable filopodia-like structures through stochastic dynamics.

Theory of mechano-chemical patterning in biphasic biological tissues

This paper introduces a biphasic model of multicellular tissues that explains pattern formation through mechano-chemical interactions, showing how mechanical forces can drive pattern formation with fewer morphogens than previously thought.