Author

U. Lendahl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Betsholtz· 3 shared L. He· 2 shared L. Muhl· 2 shared M. A. Mae· 2 shared M. Vanlandewijck· 2 shared A. Anisimov· 1 shared A. Baker· 1 shared A. Brinek· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersPathology

C. Betsholtz

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Author profile →

4 papers

Recent·Most cited

Multimodal characterization of the murine neurovascular niche using a novel microvascular isolation protocol

K. D. Bjornholm, M. Vanlandewijck, F. Del Gaudio, U. Lendahl, P. Nilsson, H. Karlström, C. Betsholtz

This paper introduces a method to isolate murine brain microvasculature without transgenic lines or FACS sorting, validated through scRNA-seq, WB, and primary culture.

bioRxiv · Aug 31, 2021 · PreprintCell Biology

Lack of evidence of ACE2 expression and replicative infection by SARS-CoV-2 in human endothelial cells

I. McCracken, G. Saginc, L. He, A. Huseynov, A. Daniels, S. Fletcher, C. Peghaire, V. Kalna, M. A. Mae, L. Muhl, N. M. Craig, S. J. Griffiths, J. G. Haas, C. T. Burkard, U. Lendahl, , A. M. Randi

The paper investigates ACE2 expression and SARS-CoV-2 infection in human endothelial cells, finding low or absent ACE2 expression and no viral replication.

bioRxiv · Dec 2, 2020Pathology

Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 - implications for microvascular inflammation and hypercoagulopathy in COVID-19

L. He, M. A. Mae, L. Muhl, Y. Sun, R. Pietila, K. Nahar, E. V. Liebanas, M. J. Fagerlund, A. Oldner, J. Liu, G. Genove, L. Zhang, Y. Xie, S. Liptidis, G. Mocci, , C. Betsholtz

The paper shows that pericytes, not endothelial cells, express ACE2 in microvessels, suggesting they may be infected in COVID-19 and contribute to microvascular inflammation and hypercoagulopathy.

bioRxiv · May 11, 2020 · PreprintPathology

DoUble resin Casting micro computed Tomography (DUCT) reveals biliary and vascular pathology in a mouse model of Alagille syndrome

S. Hankeova, J. Salplachta, T. Zikmund, M. Kavkova, N. Van Hul, A. Brinek, V. Smekalova, J. Laznovsky, J. Jaros, V. Bryja, U. Lendahl, E. Ellis, E. Hannezo, J. Kaiser, E. R. Andersson

The paper introduces DUCT, a method to image and quantify 3D biliary and vascular structures in mouse livers, revealing novel phenotypes in Alagille syndrome models and human patients.

bioRxiv · Nov 21, 2019Pathology