Author

J. Lempart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

U. Jakob· 2 shared A. Sutter· 1 shared D. Southworth· 1 shared E. Rhoades· 1 shared E. Tse· 1 shared H. E. Merens· 1 shared J. A. Lauer· 1 shared J. Murphy· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

U. Jakob

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2 papers

Recent·Most cited

Mechanistic Insights into the Protective Roles of Polyphosphate Against Amyloid Cytotoxicity

J. Lempart, E. Tse, J. A. Lauer, M. I. Ivanova, A. Sutter, N. Yoo, P. Huettemann, D. Southworth, U. Jakob

This study investigates how polyphosphate (polyP) affects α-synuclein fibril formation and cytotoxicity, finding that polyP alters fibril morphology and reduces membrane interaction, suggesting potential therapeutic applications.

bioRxiv · Jul 16, 2019Cell Biology

Polyphosphate initiates tau aggregation through intra- and intermolecular scaffolding

S. P. Wickramasinghe, J. Lempart, H. E. Merens, J. Murphy, U. Jakob, E. Rhoades

This study shows polyphosphate initiates tau aggregation by altering its conformation and enabling noncovalent cross-linking.

bioRxiv · Mar 25, 2019Biophysics