Author

J. M. Garlick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. K. Mapp· 2 shared C. L. Brooks· 2 shared A. J. Worth· 1 shared A. L. Peiffer· 1 shared A. Peiffer· 1 shared G. Tamayo-Castillo· 1 shared I. A. Blair· 1 shared J. A. Yates· 1 shared

Activity by Year

2016-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

A. K. Mapp

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3 papers

Recent·Most cited

Norstictic acid is a selective allosteric transcriptional regulator

J. M. Garlick, S. M. Sturlis, P. A. Bruno, J. A. Yates, A. Peiffer, Y. Liu, L. Goo, L. Bao, S. De Salle, G. Tamayo-Castillo, C. L. Brooks, S. D. Merajver, A. K. Mapp

This study identifies norstictic acid as a selective allosteric inhibitor of Med25-mediated transcriptional interactions, showing its effect in vitro and in a breast cancer model.

bioRxiv · Mar 26, 2021Biochemistry

TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform

A. L. Peiffer, J. M. Garlick, Y. Wu, M. B. Soellner, C. L. Brooks, A. K. Mapp

The paper identifies TMPRSS2 inhibitors using a combination of virtual screening and biochemical assays, revealing both covalent and non-covalent inhibitors.

bioRxiv · Mar 22, 2021Biochemistry

Bioorthogonal pro-metabolites for profiling short chain fatty acylation

W. R. Sinclair, T. T. Zengeya, J. M. Garlick, A. J. Worth, I. A. Blair, N. W. Snyder, J. L. Meier

This paper introduces bioorthogonal pro-metabolites to profile short chain fatty acylation in cells, identifying novel protein targets and characterizing their metabolic and enzymatic effects.

bioRxiv · Dec 30, 2016Cell Biology