Author

J. M. Gee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Vargas· 1 shared A. E. McCart Reed· 1 shared A. H. Sims· 1 shared A. Hasson· 1 shared A. J. Dalley· 1 shared A. R. Green· 1 shared A. Raghavendra· 1 shared A. Santiago-Gomez· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. C. Vargas

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2 papers

Recent·Most cited

Epigenome erosion drives neural crest-like phenotypic mimicry in triple-negative breast cancer and other SOX10+ malignancies

J. M. Saunus, X. M. De Luca, K. Northwood, A. Raghavendra, A. Hasson, A. E. McCart Reed, M. Lim, S. Lal, A. C. Vargas, J. R. Kutasovic, A. J. Dalley, M. Miranda, E. Kalaw, P. Kalita-de Croft, I. Gresshoff, , S. R. Lakhani

The paper identifies SOX10 expression in TNBC and other SOX10+ malignancies, linking it to epigenome erosion and neural crest-like phenotypic mimicry through promoter hypomethylation.

bioRxiv · Mar 30, 2021 · PreprintCancer Biology

PAK4 regulates stemness and progression in endocrine resistant ER-positive metastatic breast cancer

A. Santiago-Gomez, I. Dragoni, R. NicAmhlaoibh, E. Trivier, V. Sabin, B. M. Simoes, J. M. Gee, A. H. Sims, S. J. Howell, R. B. Clarke

This study shows PAK4 promotes stemness and progression in ER+ metastatic breast cancer and that targeting PAK4 reverses endocrine resistance.

bioRxiv · Feb 26, 2019Cancer Biology