Author

X. M. De Luca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:protein sequence· 1

Frequent Co-Authors

J. M. Saunus· 3 shared M. Lim· 3 shared P. Kalita-de Croft· 3 shared S. R. Lakhani· 3 shared P. T. Simpson· 2 shared A. C. Vargas· 1 shared A. E. McCart Reed· 1 shared A. Hasson· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersPathology

J. M. Saunus

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Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 30, 2021

Epigenome erosion drives neural crest-like phenotypic mimicry in triple-negative breast cancer and other SOX10+ malignancies

J. M. Saunus, X. M. De Luca, K. Northwood…·S. R. Lakhani

The paper identifies SOX10 expression in TNBC and other SOX10+ malignancies, linking it to epigenome erosion and neural crest-like phenotypic mimicry through promoter hypomethylation.

DOI 10.1101/2021.03.30.437624

humanbulk RNA-seq

𝕏 PostBluesky

PathologybioRxivFeb 10, 2021

Characterisation of immune cell subsets of tumour infiltrating lymphocytes in brain metastases

P. Kalita-de Croft, H. Chittoory, T. Nguyen…·S. R. Lakhani

The paper characterizes immune cell subsets in brain metastases and finds that low TILs correlate with high VISTA expression and high TILs with activated microglia.

DOI 10.3390/biology10050425

humanimaging

𝕏 PostBluesky

PathologybioRxivPreprintJan 29, 2020

Immunophenotyping of HER4/YAP axis in breast cancer brain metastasis

P. Kalita-de Croft, M. Lim, X. M. de Luca…·S. R. Lakhani

This study investigates the HER4/YAP axis in breast cancer brain metastasis using patient samples, finding HER4 phosphorylation is specific to BrM but YAP phosphorylation is not a major consequence of HER4 activation.

DOI 10.1101/2020.01.29.924118

humanprotein sequence

𝕏 PostBluesky