Cancer BiologybioRxiv
MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas
L. E. Stopfer, N. Rettko, O. Leddy…·F. White
This study shows MEK inhibition increases MHC-I antigen presentation in melanoma, enhancing immunotherapy efficacy through targeted epitopes.
DOI 10.1073/pnas.2208900119