Revealing Early Spatial Patterns of Cellular Responsivity in Fiber-Reinforced Microenvironments
S. A. Pucha, M. Hasson, H. Solomon…·J. M. Patel
This study uses PCA-AHC clustering to identify MSC subgroups with distinct responses to stiff-soft microenvironments, revealing spatial trends in cellular responsivity influenced by substrate stiffness and matrix remodeling.