Author

J. Makela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 5 Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. V. Robinson· 2 shared D. Sherratt· 2 shared J. R. Bolla· 2 shared L. K. Arciszewska· 2 shared S. Uphoff· 2 shared A. Papagiannakis· 1 shared C. Jacobs-Wagner· 1 shared D. J. Sherratt· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

C. V. Robinson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

J. Makela, A. Papagiannakis, W.-H. Lin, M. C. Lanz, S. Glenn, M. Swaffer, G. K. Marinov, J. M. Skotheim, C. Jacobs-Wagner

The paper shows genome concentration limits transcription and affects proteome composition in E. coli, with effects detectable in nutrient-rich conditions.

bioRxiv · Feb 26, 2024Cell Biology

Acyl Carrier Protein is essential for MukBEF action in Escherichia coli chromosome organization-segregation

J. P. Prince, J. R. Bolla, G. L. M. Fisher, J. Makela, C. V. Robinson, L. K. Arciszewska, D. J. Sherratt

The paper shows Acyl Carrier Protein (AcpP) is essential for MukBEF function in Escherichia coli chromosome organization-segregation.

bioRxiv · Apr 12, 2021Biochemistry

Competitive binding of MatP and topoisomerase IV to the MukB dimerization hinge

G. Fisher, J. R. Bolla, K. Rajasekar, j. makela, r. baker, m. zhou, j. prince, M. Stracy, C. V. Robinson, L. K. Arciszewska, D. Sherratt

The paper shows MatP and topoisomerase IV ParC compete for binding to the MukB dimerization hinge, with matS binding displacing MatP from the hinge.

bioRxiv · Mar 3, 2021 · PreprintBiochemistry

Non-random segregation of sister chromosomes by Escherichia coli MukBEF axial cores

J. Makela, S. Uphoff, D. Sherratt

This study shows how Escherichia coli MukBEF axial cores direct chromosome segregation and non-random inheritance through interactions with MatP and DNA replication dynamics.

bioRxiv · Jul 23, 2020 · PreprintMicrobiology

Choosing the right label for single-molecule tracking in live bacteria: Side-by-side comparison of photoactivatable fluorescent protein and Halo tag dyes

N. Banaz, J. Makela, S. Uphoff

The paper compares photoactivatable fluorescent proteins and Halo tag dyes for single-molecule tracking in live bacteria, evaluating their performance in terms of brightness, photostability, and tracking accuracy.

bioRxiv · Aug 10, 2018Biophysics