Author

D. Sherratt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

M. Stracy· 3 shared j. makela· 2 shared S. Uphoff· 2 shared A. kapanidis· 1 shared A. Maxwell· 1 shared A. Wollman· 1 shared C. Lesterlin· 1 shared C. V. Robinson· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

M. Stracy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Competitive binding of MatP and topoisomerase IV to the MukB dimerization hinge

G. Fisher, J. R. Bolla, K. Rajasekar, j. makela, r. baker, m. zhou, j. prince, M. Stracy, C. V. Robinson, L. K. Arciszewska, D. Sherratt

The paper shows MatP and topoisomerase IV ParC compete for binding to the MukB dimerization hinge, with matS binding displacing MatP from the hinge.

bioRxiv · Mar 3, 2021 · PreprintBiochemistry

Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins

M. Stracy, J. schweizer, D. Sherratt, A. kapanidis, S. Uphoff, C. Lesterlin

This study shows that bacterial DNA-binding proteins spend most of their search time bound to DNA, with frequent short-lived interactions slowing their movement through the nucleoid.

bioRxiv · Aug 13, 2020Cell Biology

Non-random segregation of sister chromosomes by Escherichia coli MukBEF axial cores

J. Makela, S. Uphoff, D. Sherratt

This study shows how Escherichia coli MukBEF axial cores direct chromosome segregation and non-random inheritance through interactions with MatP and DNA replication dynamics.

bioRxiv · Jul 23, 2020 · PreprintMicrobiology

Single-molecule imaging of DNA gyrase activity in living Escherichia coli

M. Stracy, A. Wollman, E. Kaja, J. Gapinski, J.-E. Lee, V. Leek, S. McKie, L. Mitchenall, A. Maxwell, D. Sherratt, M. Leake, P. Zawadzki

This study uses single-molecule imaging to analyze DNA gyrase activity in live E. coli, showing gyrase dynamics and supercoil regulation during replication.

bioRxiv · Nov 1, 2018Biophysics