Author

W.-H. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cell Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:E. coli· 2 Organism:human· 2

Frequent Co-Authors

C. Jacobs-Wagner· 3 shared A. Papagiannakis· 2 shared P. Z. Anastasiadis· 2 shared S. Glenn· 2 shared A. Singharoy· 1 shared C.-C. Lin· 1 shared D. Stein· 1 shared D. T. Hansen· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

C. Jacobs-Wagner

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Coupling of cell growth modulation to asymmetric division and cell cycle regulation in Caulobacter crescentus

S. Glenn, W.-H. Lin, A. Papagiannakis, S. Kato, C. Jacobs-Wagner

This study shows that Caulobacter crescentus daughter cells have different growth rates due to a G1 phase slowdown, mediated by (p)ppGpp, linking growth modulation to asymmetric division and cell cycle regulation.

bioRxiv · Apr 10, 2024 · PreprintMicrobiology

Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

J. Makela, A. Papagiannakis, W.-H. Lin, M. C. Lanz, S. Glenn, M. Swaffer, G. K. Marinov, J. M. Skotheim, C. Jacobs-Wagner

The paper shows genome concentration limits transcription and affects proteome composition in E. coli, with effects detectable in nutrient-rich conditions.

bioRxiv · Feb 26, 2024Cell Biology

Structural analyses of the plant PRT6-UBR box in the Cys-Arg/N-degron pathway and insights into the plant submergence response

L. Kim, C.-C. Lin, T.-J. Lin, Y.-C. Cao, M.-C. Chen, M.-Y. Chou, W.-H. Lin, M. Kim, J.-L. Wu, M.-C. Shih, H. K. Song, M.-C. Ho

This study determines the structure of PRT6-UBR box in rice and Arabidopsis and identifies conserved motifs critical for Cys-Arg/N-degron recognition, showing that modifying these motifs improves submergence tolerance in Arabidopsis.

bioRxiv · Aug 19, 2022 · PreprintBiochemistry

Connecting single-cell ATP dynamics to overflow metabolism, cell growth and the cell cycle in Escherichia coli

W.-H. Lin, C. Jacobs-Wagner

This study quantifies ATP dynamics in single E. coli cells and links them to growth rate, metabolism, and cell cycle, revealing that overflow metabolism drives ATP fluctuations and growth heterogeneity.

bioRxiv · May 3, 2022Cell Biology

A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma

W.-H. Lin, R. W. Feathers, L. M. Cooper, L. Lewis-Tuffin, J. N. Sarkaria, P. Z. Anastasiadis

This study identifies a Syx-RhoA-Dia1-YAP/TAZ signaling axis that promotes glioblastoma growth, DNA damage, and therapy resistance, suggesting it as a therapeutic target.

bioRxiv · Dec 3, 2021Cancer Biology

Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma

R. J. Boyd, T. Olson, J. Zook, M. Aceves, D. Stein, W.-H. Lin, F. Craciunescu, D. T. Hansen, P. Z. Anastasiadis, A. Singharoy, P. Fromme

This study characterizes human Syx, a RhoGEF involved in glioblastoma, and performs computational simulations to elucidate its structure and allosteric regulation.

bioRxiv · Aug 26, 2021Biochemistry